Surface modification: activation and deactivation of osteogenic differentiation based on detachable growth factor protein

Zhen-Yu Guan, Yi-Kai Chen, Chih-Yu Wu, Shinn-Chih Wu, Jiashing Yu, HsienYeh Chen* “Sur...
An advanced material interface is modified by using a substrate-independent coating of detachable poly-para-xylylene, enabling dynamical control of the immobilization and detachment of biomolecules, and a previously installed biological function is deactivated or tuned with reduced activity. The induction of osteogenesis activity, and subsequent deactivation of such osteogenesis activity, is demonstrated.