Abstract
![Abstract Image](https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/cmatex/2015/cmatex.2015.27.issue-20/acs.chemmater.5b02433/20151021/images/medium/cm-2015-024339_0004.gif)
An innovative intraocular lens (IOL) device was fabricated based on a chemical vapor deposition encapsulation process using functionalized poly-p-xylylenes. The advanced IOL device provides noncompromised design parameters for both its optical and biological properties. As an excellent optical device, it provides a high refractive index and a tunable effective focal length that is realized by manipulating the wetting properties of the encapsulated liquids; the device also offers protection from UV radiation. As a key medical device, it exhibits excellent biocompatibility and reduced postoperative calcification through the intrinsic properties of poly-p-xylylenes. In addition, these synergic functions are provided with precise surface chemistry for location to a guided attachment or repellent properties for eye epithelial cells, which is important in preventing device-associated complications.